Miseliminate-and-Lose, or MeLo, is a game state where the Town will lose if it miseliminates during the present Day phase. This is different from ELo in that ELo requires the Town to eliminate correctly, whereas in MeLo the Town is still afforded the opportunity to No Eliminate without forfeiting the game (though this generally makes the next Day ELo).
While the opportunity for No Elimination is available in MeLo, whether it should be done is a different question. On the upside, by refusing to eliminate the Town may be able to give its investigative roles another chance to work their magic. On the downside, if the Town has already massclaimed or if there are no roles that can make use of the Night remaining, opting not to eliminate will simply give the scum a free kill on the Townie who is most likely to help the Town eliminate correctly at ELo.